In July 1928, when the Chillicothe Baking Company in Chillicothe Missouri put its new bread slicer to use, the idea of packaged pre-sliced bread was revolutionary. The slicer was invented by a friend of the bakery's owner, a local jeweler and notorious tinkerer named Otto Rohwedder. He also came up with ways to minimize sloppy loaves and preserve freshness once a loaf had been sliced--a bread wrapping machine that immediately sealed sliced loaves in a bag.
Americans were quick to adapt. By 1930, just two years later, pre-sliced loaves could be found in every U.S. town thanks in part to Wonder Bread, which came to dominate the sliced bread market. By the 50's "best thing since sliced bread" came into the vernacular to describe new inventions like toasters and television sets. (From an article in Food & Wine)