Vitis rotundifolia (the scuppernong) is used to make wine in its native area, the Southeastern USA.
Vitis labrusca is the Fox Grape and is native to the eastern USA. It's been domesticated and several varieties are widely cultivated. The Concord grape is a labrusca variety is mostly used for unfermented grape juice, jams, and jellies. Concord, as well as Catawba and other varieties, are also used to make wine, particularly in the Northeast USA.
Vitis riparia grows wild here in New Hampshire (so does V. labrusca). A reasonable eating grape, although the fruit is small, but I don't know if it's made into wine.
Vitis rupestris is native to the Southeast USA and is the basis for many rootstock varieties, including the infamous AxR1 (a hybrid between the V. vinifera variety Aramon and V. rupestris).
-Paul W.
